Development in Health and Disease: Birth Defects, Endocrine Disruptors, and Cancer

The Role of Chance

Genetic Errors of Human Development

  • The developmental nature of human syndromes
  • Genetic and phenotypic heterogeneity

Teratogenesis: Environmental Assaults on Animal Development

  • Alcohol as a teratogen
  • Retinoic acid as a teratogen

Endocrine Disruptors: The Embryonic Origins of Adult Disease

  • Diethylstilbestrol (DES)
  • Bisphenol A (BPA)
  • Atrazine: Endocrine disruption through hormone synthesis
  • Fracking: A potential new source of endocrine disruption

Transgenerational Inheritance of Developmental Disorders

Cancer as a Disease of Development

  • Development-based therapies for cancer

Coda

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