Skip to main content

Return to Genetics student resources

Additional reading: Chapter 15

Additional Reading:

Nature Review Genetics has published a series of review articles about how genetic screens are done in different organisms.  Here are some of the references. 

Candela H, Hake S. The art and design of genetic screens: maize. Nat Rev Genet. 2008;9(3):192-203. doi: 10.1038/nrg2291.

Casselton L, Zolan M. The art and design of genetic screens: filamentous fungi. Nat Rev Genet. 2002;3(9):683-97.

Forsburg SL. The art and design of genetic screens: yeast. Nat Rev Genet. 2001;2(9):659-68.

Grimm S. The art and design of genetic screens: mammalian culture cells. Nat Rev Genet. 2004;5(3):179-89.

Jorgensen EM, Mango SE. The art and design of genetic screens: Caenorhabditis elegans. Nat Rev Genet. 2002;3(5):356-69.

Kile BT, Hilton DJ. The art and design of genetic screens: mouse. Nat Rev Genet. 2005 Jul;6(7):557-67. Review.

Page DR, Grossniklaus U. The art and design of genetic screens: Arabidopsis thaliana. Nat Rev Genet. 2002;3(2):124-36. Review.

Patton EE, Zon LI. The art and design of genetic screens: zebrafish. Nat Rev Genet. 2001 Dec;2(12):956-66. Review.

Shuman HA, Silhavy TJ. The art and design of genetic screens: Escherichia coli. Nat Rev Genet. 2003;4(6):419-31.

St. Johnston, D. The art and design of genetic screens: Drosophila melanogaster.  Nat Rev Genet. 2002 Mar;3(3):176-88.

Davis, R. H. (2003). The microbial models of molecular biology: from genes to genomes. Oxford University Press.

Hartwell, Leland H., et al. "Genetic control of the cell division cycle in yeast." Science 183 (1974): 46-51. This is the original paper. Hartwell’s reflections are on are published as

Hartwell, LH. 1991 Twenty-five years of cell cycle genetics.  Genetics 129: 975-980

Strauss, B.S., 2016.  Biochemical genetics and molecular biology: The contributions of George Beadle and Edward Tatum. Genetics 2013: 13-20. 

Winston, F. and D. Koshland, 2016.  Back to the future: Mutant hunts are still the way to go.  Genetics 203: 1007-1010.

Additional Reading for Boxes:

Toolbox 15.2

Müller-Hill, Benno. The lac operon. New York:: Walter de Gruyter, 1996.