Additional reading: Chapter 12

Additional reading: Chapter 12

Additional Reading:

Ambros, V. 2001 microRNAs: Tiny regulators with great potential.  Cell 107: 823-826 The literature on microRNAs is very large but this relatively early summary of microRNA research by one of the investigators who discovered them is helpful. 

Hawkins RD, Hon GC, Ren B. Next-generation genomics: an integrative approach. Nat Rev Genet. 2010 Jul;11(7):476-86. doi: 10.1038/nrg2795.

Hoheisel, JD 2006.  Microarray technology: Beyond transcript profiling and genotype analysis.  Nat. Rev. Genet. 7: 200-210. 

Vaharoutio A. and J Taipale. 2014.  Cancer by super-enhancer. Science 346: 1291-1292.  A very brief review that introduces the importance of enhancer mutations in human cancers, with clear figures. 

Additional Reading for Boxes:

Toolbox 12.2

Boutros M, Ahringer J. The art and design of genetic screens: RNA interference. Nat Rev Genet. 2008 Jul; 9(7):554-66. doi: 10.1038/nrg2364. Review. PubMed PMID: 18521077.

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