Chapter 28 Further reading

Manipulating DNA and genes

• Tucker, T., Marra, M., and Friedman, J.M. (2009). Massively parallel sequencing: The next big thing in genetic medicine. Am. J. Hum. Genet., 85, 142–54.

The potential and challenges for the application of modern sequencing technology to medicine.

• Berlec, A., and Strukelj, B. (2013). Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells. J. Ind. Microbiol. Biotechnol., 40, 257–74.

A general update on the expression of recombinant proteins.

• Terns, R.M., and Terns, M.P. (2014). CRISPR-based technologies: prokaryotic defense weapons repurposed. Trends in Genetics, 30, 111–18.

A fairly concise review that covers both the biological function of CRISPR systems and their adaptation for experimental and therapeutic purposes. 

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